Undergraduate Specialization - Endocrinology
After taking the following three courses, students
majoring in biological sciences will be recognized as having completed
a specialization in endocrinology. Students who complete the
specialization will be well versed in all aspects of endocrinology,
ranging from basic cell signaling to the integration of endocrine
systems and their dysregulation in human disease. Students will also
have the option of participating in a hands-on research component in an
endocrinology lab. The prerequisite for these courses is completion of
the Fundamentals Sequence, and prior completion of a biochemistry
course is strongly recommended. However, the specialization can be
completed either as Endocrinology I, II, III or as Endocrinology II,
III, I:
25226. Endocrinology I: Cell
Signaling. (=CPHY 33600, NPHP 33600) PQ: BIOS 20200. The subject matter
of this course considers the wide variety of intracellular mechanisms
that, when activated, change cell behavior. We cover aspects of
intracellular signaling, the latter including detailed discussions of
receptors, G-proteins, cyclic nucleotides, calcium and calcium-binding
proteins, phosphoinositides, protein kinases, and phosphatases. M.
Brady, C. Palfrey, M. Roe, J. Sun. Autumn.
25227. Endocrinology II:
Systems and Physiology. PQ: A Fundamentals Sequence (BIOS 20180s or
20190s, or AP 5 sequence). Endocrinology is the study of hormones,
which are chemical messengers released by tissues that regulate the
activity of other cells in the body. This course covers the classical
hormone systems, including hormones regulating metabolism, energy
mobilization and storage, calcium and phosphate metabolism,
reproduction, growth, “fight or flight,” and circadian rhythms. We
focus on historical perspective, the mechanisms of action, homeostatic
regulation, and relevant human diseases for each system. M. Brady, R.
Cohen. Winter.
25228. Endocrinology III:
Human Disease. A Fundamentals Sequence (BIOS 20180s or 20190s, or AP 5
sequence) and BIOS 25227 recommended but not required. This course is a
modern overview of the patho-physiologic, genetic, and molecular basis
of human diseases with nutritional perspectives. We discuss human
diseases (e.g., hypertension, cardiovascular diseases, obesity,
diabetes, osteoporosis, alopecia). Y. C. Li, M. Musch. Spring.
The specialization in endocrinology is administered by
the Sections of Adult and Pediatric Endocrinology, and the Committee on
Molecular Metabolism and Nutrition. For more information, consult
Matthew Brady (mbrady@medicine.bsd.uchicago.edu).
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