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Appointments:
Professor
Department of Surgery
Director, Center for the Surgical Treatment of Obesity
Director, Minimally Invasive Surgery & Surgical Treatment of Obesity Programs
Committee on Molecular
Metabolism and Nutrition
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Education:
M.D., Autonomous University, Guadalajara, Mexico
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Contact:
Phone: (773) 702-4876
Fax: (773) 702-0201
E-Mail:
jalverdy@surgery.bsd.uchicago.edu
Address:
The University of Chicago
AMB G201 / MC 6090
5841 South Maryland Ave.
Chicago, Illinois 60637
Webpage (Dept. of Surgery)
Webpage (Medical Center)
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Related Research Interests:
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John Alverdy, M.D.
Research Summary
As chief of the University of Chicago Medical Center's Surgical Obesity Program, Dr. John Alverdy oversees one of the most active weight loss programs in the area. He is a nationally recognized surgeon and has a vast experience in weight loss surgery--both traditional and laparoscopic.
Considered a surgical innovator, Dr. Alverdy was the first surgeon in the area to perform gastric bypass surgery and duodenal switch surgery using minimally invasive laparoscope techniques.
Dr. Alverdy is also an expert in other abdominal surgeries, including the surgical treatment of gastroesophageal reflux, hernias, colorectal diseases, and biliary tract disease.
Selected Papers
Arvans DL, Vavricka SR, Ren H, Musch MW, Kang L, Rocha FG, Lucioni A, Turner JR, Alverdy J, Chang EB. Luminal bacterial flora determines physiological expression of intestinal epithelial cytoprotective heat shock proteins 25 and 72. Am J Physiol Gastrointest Liver Physiol 2005; 288(4):G696-704
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Kohler JE, Zaborina O, Wu L, Wang Y, Bethel C, Chen Y, Shapiro J, Turner JR, Alverdy JC. Components of intestinal epithelial hypoxia activate the virulence circuitry of Pseudomonas. Am J Physiol Gastrointest Liver Physiol 2005; 288(5):G1048-54
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Buser A, Dymek-Valentine M, Hilburger J, Alverdy J. Outcome following gastric bypass surgery: impact of past sexual abuse. Obes Surg 2004; 14(2):170-4
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Clayburgh DR, Rosen S, Witkowski ED, Wang F, Blair S, Dudek S, Garcia JG, Alverdy JC, Turner JR. A differentiation-dependent splice variant of myosin light chain kinase, MLCK1, regulates epithelial tight junction permeability. J Biol Chem 2004; 279(53):55506-13
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Green AE, Dymek-Valentine M, Pytluk S, Le Grange D, Alverdy J. Psychosocial outcome of gastric bypass surgery for patients with and without binge eating. Obes Surg 2004; 14(7):975-85
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Wu L, Zaborina O, Zaborin A, Chang EB, Musch M, Holbrook C, Shapiro J, Turner JR, Wu G, Lee KY, Alverdy JC. High-molecular-weight polyethylene glycol prevents lethal sepsis due to intestinal Pseudomonas aeruginosa. Gastroenterology 2004; 126(2):488-98
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Alverdy JC, Laughlin RS, Wu L. Influence of the critically ill state on host-pathogen interactions within the intestine: gut-derived sepsis redefined. Crit Care Med 2003; 31(2):598-607
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Sanchez-Johnsen LA, Dymek M, Alverdy J, le Grange D. Binge eating and eating-related cognitions and behavior in ethnically diverse obese women. Obes Res 2003; 11(8):1002-9
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Wu L, Holbrook C, Zaborina O, Ploplys E, Rocha F, Pelham D, Chang E, Musch M, Alverdy J. Pseudomonas aeruginosa expresses a lethal virulence determinant, the PA-I lectin/adhesin, in the intestinal tract of a stressed host: the role of epithelia cell contact and molecules of the Quorum Sensing Signaling System. Ann Surg 2003; 238(5):754-64
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Dymek MP, Le Grange D, Neven K, Alverdy J. Quality of life after gastric bypass surgery: a cross-sectional study. Obes Res 2002; 10(11):1135-42
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Musch MW, Bookstein C, Rocha F, Lucioni A, Ren H, Daniel J, Xie Y, McSwine RL, Rao MC, Alverdy J, Chang EB. Region-specific adaptation of apical Na/H exchangers after extensive proximal small bowel resection. Am J Physiol Gastrointest Liver Physiol 2002; 283(4):G975-85
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Neven K, Dymek M, leGrange D, Maasdam H, Boogerd AC, Alverdy J. The effects of Roux-en-Y gastric bypass surgery on body image. Obes Surg 2002; 12(2):265-9
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Posner MC, Alverdy J. Hand-assisted laparoscopic surgery for cancer. Cancer J 2002; 8(2):144-53
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Boogerd A, Alverdy J, Kumar S, Olson DL, Schwenk WF. Part III. Obesity. Dis Mon 2002; 48(11):725-42
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Rocha F, Laughlin R, Musch MW, Hendrickson BA, Chang EB, Alverdy J. Surgical stress shifts the intestinal Escherichia coli population to that of a more adherent phenotype: role in barrier regulation. Surgery 2001; 130(1):65-73
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Buell JF, Alverdy J, Newell KA, Yoshida A, Limsrichamrern S, Woodle ES, Bruce DS. Hand-assisted laparoscopic live-donor nephrectomy. J Am Coll Surg 2001; 192(1):132-6
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Dymek MP, le Grange D, Neven K, Alverdy J. Quality of life and psychosocial adjustment in patients after Roux-en-Y gastric bypass: a brief report. Obes Surg 2001; 11(1):32-9
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Laughlin RS, Musch MW, Hollbrook CJ, Rocha FM, Chang EB, Alverdy JC. The key role of Pseudomonas aeruginosa PA-I lectin on experimental gut-derived sepsis. Ann Surg 2000; 232(1):133-42
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Factor P, Ridge K, Alverdy J, Sznajder JI. Continuous enteral nutrition attenuates pulmonary edema in rats exposed to 100% oxygen. J Appl Physiol 2000; 89(5):1759-65
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Alverdy J, Holbrook C, Rocha F, Seiden L, Wu RL, Musch M, Chang E, Ohman D, Suh S. Gut-derived sepsis occurs when the right pathogen with the right virulence genes meets the right host: evidence for in vivo virulence expression in Pseudomonas aeruginosa. Ann Surg 2000; 232(4):480-9
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| Alverdy J, Vargish T, Desai T, Frawley B, Rosen B. Laparoscopic intracavitary debridement of peripancreatic necrosis: preliminary report and description of the technique. Surgery 2000; 127(1):112-4 |
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Faculty and Research
Programs
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