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Appointments:
Associate Professor
Department of Medicine
Section of Genetic Medicine
Department of Pathology/MPMM
Director, Center for Biomedical
Informatics
Associate Director, UCCRC
Committee on Molecular Medicine/MPMM
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Education:
MD, University of Sherbrooke, 1988
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Contact:
Phone: (773) 834-0743
Fax: (773)
702-2567
E-Mail: lussier@medicine.bsd.uchicago.edu
Address:
The University of Chicago
AMB N660B, (MC 6091)
5841 South Maryland Avenue
Chicago, IL 60637
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Related Research Interests:
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Yves Lussier, M.D.
Research Summary
Dr. Lussier's research group focuses on the development
and use of high throughput phenotyping technologies to integrate and
analyze genomes with phenotypes and to accurately individualize the
prediction and the treatment of diseases. More specifically, he has
developed automated computational methods that bring together the
fields of molecular bioinformatics, ontologies, and natural language
processing in order to code, integrate, structure and mine the
escalating wealth of complex and heterogeneous phenotypes. Contributing
to the emerging field of “systems medicine”, these methods bridge the
“phenotype gap”, as phenotypes are amassed in diverse and
insufficiently related clinical, post-genomic and model organism
databases.
Selected Papers
Lussier YA; Rothwell DJ;
Côté RA. (1998). "The SNOMED Model: A Knowledge Source for
the
Controlled Terminology of the Computerized Patient Record". Methods of
Information in Medicine 37;160-164
Lussier YA, Williams R, Jalan S, Borlawsky T, Li J, Stern E.
Partitioning Knowledge Bases Between Advanced Notification and Clinical
Decision Support Systems. (accepted for the special issue on "Decision
Support in Medicine" of the journal “Decision Support Systems”).
Cantor MN, Sarkar IN, Bodenreider O, Lussier YA. (2005). Genestrace:
Phenomic
Knowledge Discovery Via Structured Terminology. Pac Symp Biocomput.
103-14
Tao Y, Friedman C, Lussier YA. (2005). “Visualizing information across
multidimensional post-genomic structured and textual databases”
Bioinformatics. 15;21(8):1659-67. Epub 2004 Dec 14
Lussier YA, Rappaport D, Borlawsky T, Friedman C. (2006). PhenoGO: a
Multistrategy Language Processing System Assigning Phenotypic Context
to Gene Ontology Annotations. Pacific Symposium on Biocomputing 64-75 |
Faculty and Research
Programs
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