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Appointments:
Professor of Surgery (Plastic)
Professor of Medicine (Dermatology)
Professor of Organismal Biology
and Anatomy (Biomechanics)
Committee on Molecular Medicine/MPMM
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Education:
Ph.D., Massachusetts Institute of
Technology, 1979
M.D., Temple University, 1975
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Contact:
Phone: (773) 702-6302
Fax:
(773) 702-1634
E-Mail: rlee@surgery.bsd.uchicago.edu
Research Website:
http://etrp.bsd.uchicago.edu
Address:
The University of Chicago
SBRI J641 (MC 6035)
5841 South Maryland Avenue
Chicago, Illinois 60637
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Related Research Interests:
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Raphael Lee, Ph.D., M.D., Sc.D.
Research Summary
In general, electromagnetic
(including ionizing) fields on tissue
growth, repair and morphogenesis. Specifically areas of active focus
are therapeutic approaches to restore cell organelle structural
integrity following exposure to extensive ionizing radiation injury
levels ranging from sunburn to nuclear power plant diasters like
Chernobyl. (see: http://etrp.bsd.uchicago.edu) The research team has
developed biocompatible surfactant copolymers that seal disrupted cell
membranes . Others surfactants were discovered to chaperone refolding
of denatured proteins which would be of particular important in skin
diseases.
Selected Papers
Journal Articles
Greenebaum B, Blossfield K, Carrillo CS, Hannig J, Beckett MA,
Weichselbaum RR, and Lee RC. (2004). Poloxamer 188 Prevents Acute
Necrosis of Adult Skeletal Muscle Fibers after High-dose Irradiation
Burns. 30(6): 539-547.
Roseborough IE, Grevious MA and Lee RC. Prevention and Treatment of
Excessive Dermal Scaring. (2004). J Natl Med Assoc., 96(1):108-16.
Cooke GL, Chien A, Brodsky A and Lee RC. (2005). Is the Incidence of
Hypertrophic Scars among African-Americans Linked to Vitamin D3
Metabolism? J Nat’l Med Assoc., 97(7):1004-9.
Despa F, Orgill DP, Neuwalder J and Lee
RC. (2005). Effects of Crowding on the Thermal Stability of
Heterogeneous Protein Solutions.
Ann. Biomed Engineering, 33(8):1125-1131.
Lee RC, Despa F, Hamann KT. (2006). Cell
Injury:
Mechanisms, Responses and Repair. Annals of the New York Acad. of
Science, Vol. 1066.
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Faculty and Research
Programs
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